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Figure 3 | Molecular Cancer

Figure 3

From: Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance

Figure 3

PTEN-knockdown reduces sensitivity to cisplatin-induced apoptosis. ACHN cells stably transfected with PTEN-shRNA (black bars) or pSuper empty vector control (gray bars) were incubated with the indicated concentrations of cisplatin for 24 h. Caspase-3 activity was measured as an indicator of apoptosis as described in Materials and Methods.

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Molecular Cancer

ISSN: 1476-4598