Genome and transcriptome profiles of cell line model. A) Genomic changes in three cell lines IS1, IS2, and IS3 from a primary carcinoma, its corresponding liver- and peritoneal metastases derived from the same patient. B) Genes expressed in fold change above 2.0 in the same cell lines. 609 genes are found in common between the three cell lines, whereas 263 genes are shared between IS1 and IS2, 130 genes in common between IS1 and IS3, and 225 genes are shared between the metastases cell lines, IS2 and IS3. 551- (IS1), 406- (IS2), and 484 genes (IS3) are only seen in one cell line.