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Table 3 Genes (n = 20), located to chromosome arm 5p that are upregulated in carcinomatoses.

From: Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses

Genebank Acc Gene Symbol Gene Name Fold change carcinomatoses Fold change liver Folde change primary Fold change carcinomatoses as compared to liver and primary
L28175 PTGER4 Prostaglandin E receptor 4 (subtype EP4) 1.02 -4.41 -2.03 4.24
AK024116 FLJ14054 Hypothetical protein FLJ14054 1.20 -2.06 -3.46 3.96
AB061834 RPL37 Ribosomal protein L37 3.62 -1.02 1.04 3.61
BC000518 BASP1 Brain abundant, membrane attached signal protein 1 1.18 -1.96 -1.65 2.98
AF155135 RAI14 Retinoic acid induced 14 1.78 -1.35 -1.02 2.96
AF064876 HCN1 Hyperpolarization activated cyclic nucleotide-gated potassium channel 1 1.53 -1.31 -1.18 2.77
AK001989 FLJ11127 Hypothetical protein FLJ11127 1.25 -1.16 -1.52 2.58
BC008752 ZNF622 Zinc finger protein 622 1.29 -1.36 -1.05 2.49
AB020647 FBXL7 F-box and leucine-rich repeat protein 7 1.43 -1.03 -1.09 2.49
AK025310 FLJ21657 Hypothetical protein FLJ21657 1.07 -1.62 -1.15 2.45
U28043 SLC9A3 Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 1.01 -1.45 -1.39 2.43
BC001380 SDHA Succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.34 -1.04 -1.05 2.39
AF338650 PDZK3 PDZ domain containing 3 1.02 -1.68 -1.02 2.37
AB019494 NIPBL Nipped-B homolog (Drosophila) 1.28 -1.13 -1.03 2.36
AF009301 MARCH-VI Membrane-associated RING-CH protein VI 1.15 -1.32 -1.06 2.34
BC022339 PC4 Activated RNA polymerase II transcription cofactor 4 1.12 -1.28 -1.07 2.30
BC003353 MGC5309 Hypothetical protein MGC5309 1.15 -1.18 -1.08 2.27
AF189011 RNASE3L Nuclear RNase III Drosha 1.04 -1.35 -1.07 2.26
BC017586 MGC26610 Hypothetical protein MGC26610 1.17 -1.08 -1.06 2.24
AY029177 SKP2 S-phase kinase-associated protein 2 (p45) 1.04 -1.00 -1.07 2.08
  1. Ratios; expression in fold change using medians of each group as compared to normal colonic tissue. Fold change carcinomatoses; expression fold in carcinomatoses – (fold in liver metastases + primaries)/2.
  2. Genes in bold are upregulated in the carcinomatoses cell line IS3.