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Figure 4 | Molecular Cancer

Figure 4

From: Calcium-activated potassium channels mediated blood-brain tumor barrier opening in a rat metastatic brain tumor model

Figure 4

Measurement of functional KCa channels activity in CRL-5904 cells and HBMEC. Membrane potential changes in relative fluorescence units (RFU) were detected during a 300-second response to 25 μM of NS1619 (A) and BK (B) respectively on the CRL-5904 cells. NS1619 and BK also elicited membrane potential changes on HBMEC (C, D). Addition of IBTX (20 nM) reversed the membrane potential to resting values.

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