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Table 1 Comparison of proteomic biomarkers and current tumor markers

From: Contribution of oncoproteomics to cancer biomarker discovery

Cancer Proteomic biomarkers Current tumor markers
  Sensitivity Specificity Reference Markers Sensitivity Specificity
Bladder 80% 90–97% [87] NMP22 31% 95%
Breast 93% 91% [88] CA 15-3 63% 80–88%
Colorectal 91% 93% [89] CEA 43% ****
Gastric 83% 95% [90] CEA 49% ****
Liver 94% 86% [91] AFP 50% 90%
Lung 87% 80% [92] Cyfra21-1 63% 94%
Ovarian 83% 94% [93] CA-125 57% ****
Pancreatic 78% 97% [94] CA 19-9 72% ****
Prostate 83% 97% [95] PSA 86% 20–34%