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Table 2 Markers expressed in normal and cancer stem cells in humans

From: Mismatch repair deficiencies transforming stem cells into cancer stem cells and therapeutic implications

Organ

Cancer type

Normal stem cell markers

Cancer stem cell markers

References

Hematopoietic

Leukemia

CD34+CD38-Thy1-Lin-

CD34+CD38- Thy1-Lin-

[47, 48]

Breast

Mammary cancer

CD24med

CD44+CD24-/lowESA+Lin-

[8, 11]

Brain

Brain tumor

CD133+Lin-

CD133+ Nestin

[49, 50]

Skin

Melanoma cancer

CD20-CD166- Nestin-

CD20+ CD166+ Nestin+

[51, 52]

Prostate

Prostate cancer

CD133+α2β1hi

CD44+α2β1hiCD133+

[53]

Tongue, Larynx, Throat and Sinus

Head and neck squamous cell carcinoma (HNSCC)

CD44-

CD44+

[54]

Pancreas

Pancreatic cancer

CD24-CD44-ESA-

CD24+ CD44+ESA+

[48]