Figure 4
From: HHV-8 encoded LANA-1 alters the higher organization of the cell nucleus
LANA-1 expression does not effect 3MK9H3 (green) levels as measured using extended field laser scanning microscopy (EFLCM) that automatically captured 300 adjacent fields as a mosaic of Z projected images of 12 optical sections each. The total fluorescence intensity measurement for 3MK9H3, DNA (blue) and LANA-1 (red) of the individual nuclei is plotted in the order of increasing amount of LANA-1. The amount of 3MK9H3 staining is also compared on population levels of LANA-1 positive and negative nuclei on a box chart.