Pre-apoptotic response to therapeutic DNA damage involves protein modulation of Mcl-1, Hdm2 and Flt3 in acute myeloid leukemia cells

Table 1 Clinical and biological characteristics of AML patients

Patients	Age	Sex	Previous malignant disease	FAB	Membrane molecules					Karyotype	*FLT3 LM*	*FLT3 Asp835*	Survival (Weeks)
					CD 13	CD 14	CD 15	CD 33	CD 34
# 1	72	M	Residive	AML M1	+	-	+	+	-	Normal	wt	wt	6
# 2	34	F	-	AML M5a	-	-	+	+	-	46 XX, t(9;11), (q22;q23)	wt	0.31	>24 (Tx)
# 3	55	M	-	Atypical	+	-	+	+	-	Multiple	wt	wt	>23

The patients were randomly selected; their clinical and biological data are included as background information.

ISSN: 1476-4598