Figure 5From: A doxycycline-inducible urokinase receptor (uPAR) upregulates uPAR activities including resistance to anoikis in human prostate cancer cell linesEffect of induced uPAR expression on proliferation. Prostate cancer cells were either uninduced or induced to express uPAR-DsRed with 1.0 ug/mL doxycycline. DsRed-expressing cells were used as a growth control. Cells were plated at 10,000 cells per well in 24-well plates and grown in culture medium containing 2% fetal bovine serum with (+) or without urokinase (uPA; 100 pM). Medium was changed during the third day. Symbols and indicated conditions are: ◆ uninduced, without uPA; × uninduced plus uPA; △ doxycycline induced without uPA; ■ doxycycline induced plus uPA; □ DsRed control without uPA; ● DsRed control plus uPA. Data reflects the means of 4 wells. Bars, SE.Back to article page