Figure 6From: A doxycycline-inducible urokinase receptor (uPAR) upregulates uPAR activities including resistance to anoikis in human prostate cancer cell linesEffect of induced uPAR expression on adhesion to vitronectin. Adhesion of prostate cancer cells to vitronectin is increased by induction of uPAR by doxycycline. Prostate cancer cells from wild-type control cultures (grey bars), DsRed-expressing controls (striped bars), un-induced cultures (white bars) and uPAR-induced cells (black bars) were plated into vitronectin-coated wells in a 24-well plate. Following a one-hour period of attachment, the cells were detached and counted as described in Methods. Data is expressed as the number of adherent cells per well; error bars show the SD from quadruplicate wells.Back to article page