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Table 1 Zip2 immunopositivity of glandular components in prostate tissue sections.

From: hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands

Case noa.

Zip2 IHC SCOREb

 

Normal

BPH

Malignant

1

+++

+++

-

2

N/A

++

-

3

N/A

++

-

4

N/A

++

-

5

N/A

++

-

6

+++

+++

-

7

+++

++

+

8

N/A

++

++

9

++

+

-

11

N/A

++

-

12

N/A

+

-

13

N/A

++

-

14

N/A

+

-

15

N/A

+

-

16

N/A

-

-

17

N/A

-

-

18

N/A

+++

-

20

N/A

-

-

21

N/A

++

-

22

N/A

+++

-

23

N/A

-

-

24

N/A

+++

N/A

25

++

++

-

26

N/A

++

-

27

N/A

+++

+

Neg Zip2 IHC

0/5

4/25

21/24*

Scores > +

5/5

17/25

1/24*

Mean score c

2.60

1.76

0.17*

  1. aCase number: Cases 1–23 are the same cases from our previous studies [6,8]. Cases from 24–27 are new cases.
  2. bScoring of immunoreactivity was done as follows: negative, no positive cells; score +, < 10% positive cells; score ++, 10–50% positive cells; score +++, > 50% positive cells.
  3. cMean score: Mean for each group was obtained by the sum of the +'s/number of cases.
  4. *P < 0.001 for malignant vs normal or vs BPH.