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Table 1 Zip2 immunopositivity of glandular components in prostate tissue sections.

From: hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands

Case noa. Zip2 IHC SCOREb
  Normal BPH Malignant
1 +++ +++ -
2 N/A ++ -
3 N/A ++ -
4 N/A ++ -
5 N/A ++ -
6 +++ +++ -
7 +++ ++ +
8 N/A ++ ++
9 ++ + -
11 N/A ++ -
12 N/A + -
13 N/A ++ -
14 N/A + -
15 N/A + -
16 N/A - -
17 N/A - -
18 N/A +++ -
20 N/A - -
21 N/A ++ -
22 N/A +++ -
23 N/A - -
24 N/A +++ N/A
25 ++ ++ -
26 N/A ++ -
27 N/A +++ +
Neg Zip2 IHC 0/5 4/25 21/24*
Scores > + 5/5 17/25 1/24*
Mean score c 2.60 1.76 0.17*
  1. aCase number: Cases 1–23 are the same cases from our previous studies [6,8]. Cases from 24–27 are new cases.
  2. bScoring of immunoreactivity was done as follows: negative, no positive cells; score +, < 10% positive cells; score ++, 10–50% positive cells; score +++, > 50% positive cells.
  3. cMean score: Mean for each group was obtained by the sum of the +'s/number of cases.
  4. *P < 0.001 for malignant vs normal or vs BPH.