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Table 2 Confirmation of microarray findings by real-time RT-PCR*

From: Androgen-regulated genes differentially modulated by the androgen receptor coactivator L-dopa decarboxylase in human prostate cancer cells

 

R1881 ±

R1881 ±

  

Symbol

ARRAY DDC

ARRAY controls

RT-PCR DDC

RT-PCR control

ARRAY DDC/controls

RT-PCR DDC/control

TGM2

4.7

2.2

36.7

25.2

+2.1

+1.5

TMEPAI

4.8

2.3

17.8

10.6

+2.1

+1.7

PTGDR

2.2

0.4

1.5

0.5

+5.3

+3.0

YME1L1

2.6

0.1

1.3

0.8

+21.4

+2.5

SYTL2

0.3

0.5

0.2

0.3

- 2.0

- 1.5

DRD3

0.1

0.3

0.5

0.9

- 4.3

- 1.8

  1. * In bold are represented the fold changes of hormone up-regulated genes and in italic the fold changes of hormone down-regulated genes, after R1881 treatment. The symbols +/- indicate the fold induction (+) or repression (-) due to DDC overexpression.