Skip to main content

Table 4 Effect of the NO donor SNAP on the hydrolysis of Abz-GFSPFRQ-EDDnp by rTOP

From: Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth

SNAP

Hydrolysis (%)1

Control (no inhibitor)

100

1 mM

38 ± 3

500 μM

50 ± 3

250 μM

83 ± 4

100 μM

98 ± 2

1 mM + DTT 0.5 mM

100 ± 1

  1. 1100% hydrolysis represents the cleavage of 20 μM of Abz-GFSPFRQ-EDDnp by rTOP during 5 min at 37°C in 50 mM Tris-HCl, pH 7.4.
Back to article page

Molecular Cancer

ISSN: 1476-4598