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Figure 2 | Molecular Cancer

Figure 2

From: DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets

Figure 2

Representative methylation-specific polymerase chain reaction (MSP) results from primary ovarian carcinomas. PCR products in lane U indicate the presence of unmethylated alleles whereas PCR products in lanes M indicate the presence of methylated alleles. Panel A illustrates HOXA9 (the upper bands represent MSP products, whereas the lower bands are excess primers). Panel B illustrates SCGB3A1. Abbreviation: Pos, positive control (DNA from normal blood is used as control for unmethylated samples, and in vitro methylated DNA is used as control for methylated samples); Neg, negative control (template replaced by water); Lane 1–6, individual ovarian carcinomas; 100 bp DNA marker from Promega Corp, Madison, WI, USA. The illustration has been processed from a photo including more samples. Hence, the controls have been moved from their original position and pasted adjacent to the selected samples shown here.

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Molecular Cancer

ISSN: 1476-4598