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Figure 3 | Molecular Cancer

Figure 3

From: Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy

Figure 3

AICAR treatment induces cell cycle arrest in G1-phase in ALL cells. DNA content of CCRF-CEM, NALM6, REH, and SupB15 ALL cells untreated (Control) or treated with AICAR (0.5 and 2.0 mM) for 48 h was measured by fluorescence-activated cell sorting (FACS) using propidium iodide staining. The panels represent distribution of cells (%) in G1-, S-, and G2-phase of the cell cycle obtained from FACS analysis. Data are representative of at least three independent experiments and values are expressed as mean ± SEM.

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Molecular Cancer

ISSN: 1476-4598