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Figure 5 | Molecular Cancer

Figure 5

From: Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma

Figure 5

Scheme of pathways involved in trisomy 19 ependymoma. Cancer occurs because of accumulation of defects implying cell cycle, cell proliferation, differentiation, apoptosis, cell interaction with surrounding stroma and angiogenesis. All these pathways could be deregulated when considering genes located in the 4 chromosomic regions most frequently altered in trisomy 19 ependymomas.

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Molecular Cancer

ISSN: 1476-4598