|
HER-2/neu statusb
|
Lymph node
|
---|
Intensitya
|
Positive (n = 21)
|
Negative (n = 68)
|
p
|
Positive (n = 36)
|
Negative (n = 53)
|
p
|
pSer78
| | | | | | |
N
|
2
|
30
| |
8
|
24
| |
P
|
19
|
38
|
0.004
|
28
|
29
|
0.026
|
pSer82
| | | | | | |
N
|
8
|
40
| |
20
|
28
| |
P
|
13
|
28
|
0.096
|
16
|
25
|
0.800
|
pSer15
| | | | | | |
N
|
15
|
53
| |
26
|
42
| |
P
|
6
|
15
|
0.539
|
10
|
11
|
0.444
|
Hsp27
| | | | | | |
N
|
3
|
26
| |
13
|
16
| |
P
|
18
|
42
|
0.041
|
23
|
37
|
0.558
|
- astaining level was defined as negative for negative/weak staining and positive for moderate and strong staining. P: positive; N: negative. bHER-2/neu status was described based on FISH: the cutoff value for positive is ≥ 2:1 (HER-2 locus: CEP-17). p value was calculated from the chi-square test. Significance was set at p < 0.05.