Functional categories affected by cisplatin exposure of TGCT cells. Hierarchical clustering analysis of significantly enriched (p < 0.01) GO-terms. SAM-identified differentially expressed genes (n = 1794) were grouped into gene sets based on common biological processes, molecular functions, or cellular components as assessed by the GO database. The average gene expression ratios of the gene sets in each GO term were used to construct the heat-map. Color coding: Over-represented GO-terms in the over-expressed gene sets (red), and over-represented terms in the under-expressed gene sets (green).