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Table 2 Predictors of microsatellite status identified by Support Vector Machine and PAM algorithms.

From: mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer

Probe Symbol   Average expression p-value SVM* strength PAM* score
   Gene name MSS MSI-H    MSI-H MSS
hsa-mir-223-prec miR-223   0.97 1.84 4.69E-02 - 0.4929 -0.3429
hsa-mir-155-prec miR-155 (BIC)   0.97 1.29 2.34E-02 - 0.4439 -0.3088
AL137343 FAM84A family with sequence similarity 84, member A 1.51 0.45 1.07E-02 - -0.0208 0.0145
NM_004183 VMD2 vitelliform macular dystrophy 2 2.09 0.38 8.73E-03 - -0.1832 0.1274
NM_006113 VAV3 vav 3 oncogene 1.62 0.47 5.98E-03 13.96 -0.0533 0.0371
NM_005953 MT2A metallothionein 2A 0.57 1.92 5.93E-03 16.34 0.8995 -0.6258
AK026372 KIAA1718   1.27 0.72 5.09E-03 16.02 - -
hsa-mir-191-prec miR-191   1.28 1.00 4.74E-03 - 0.0377 -0.0263
NM_017726 PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 1.31 0.52 3.88E-03 14.58 - -
NM_003212 TDGF1 teratocarcinoma-derived growth factor 1 1.49 0.76 3.37E-03 16.49 - -
AF273051 CCDC68 coiled-coil domain containing 68 2.21 0.84 2.49E-03 15.87 -0.0541 0.0376
NM_016328 GTF2IRD1 GTF2I repeat domain containing 1 1.49 0.87 2.13E-03 13.13 - -
NM_001657 AREG amphiregulin 2.10 0.69 1.04E-03 - -0.0725 0.0504
AB033045 KIAA1219 hypothetical protein LOC57148 1.33 0.83 8.11E-04 15.87 - -
hsa-mir-032-precNo2 miR-032   1.17 0.91 6.48E-04 14.02 0.0732 -0.0509
NM_004485 GNG4 guanine nucleotide binding protein (G protein), gamma 4 1.46 0.81 6.47E-04 16.49 - -
NM_018267 H2AFJ H2A histone family, member J 1.43 0.92 6.47E-04 13.96 - -
AK000276 NKD1 naked cuticle homolog 1 2.47 0.77 4.55E-04 17.48 -0.1542 0.1072
NM_003878 GGH gamma-glutamyl hydrolase 2.10 0.61 7.97E-05 15.87 -0.2232 0.1553
AK025215 C13ORF18 chromosome 13 open reading frame 18 2.41 0.66 4.40E-05 16.49 -0.3093 0.2152
NM_017763 RNF43 ring finger protein 43 2.10 0.57 2.91E-05 17.48 -0.2886 0.2008
NM_004693 K6HF cytokeratin type II 1.24 0.80 2.91E-05 14.6 - -
NM_002657 PLAGL2 pleiomorphic adenoma gene-like 2 1.37 0.76 2.91E-05 19.32 - -
hsa-mir-025-prec miR-025   1.52 0.84 2.14E-05 17.48 - -
hsa-mir-092-prec-13=092-1No2 miR-092-1   1.50 0.65 1.87E-05 17.48 - -
hsa-mir-092-prec-X=092-2 miR-092-2   1.60 0.64 1.87E-05 14.43 - -
hsa-mir-093-prec-7.1=093-1 miR-093-1   1.23 0.9 1.87E-05 - 0.0084 -0.0058
  1. * SVM: Support Vector Machine; PAM: Prediction Analysis of Microarray