Figure 5
From: Nilotinib treatment in mouse models of P190 Bcr/Abl lymphoblastic leukemia
Long term viability of three lymphoma cell lines 8093, A-5 and A-21 treated with 20 nM nilotinib either in the presence (A) or absence (B)of irradiated stroma (mouse E14.5 embryonic fibroblasts). 3 × 106 lymphoma cells were seeded in 6 well tissue culture plates and treated with 20 nM nilotinib. Fresh drug was added every third day with the change of medium. Viability was assessed by the Trypan Blue exclusion method and is expressed as percentage of viable cells/total cells. Each point represents the average of triplicate values ± SEM.