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Figure 3 | Molecular Cancer

Figure 3

From: Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized

Figure 3

Supervised Clustering of Pre-stasis, and Post-selection HMEC. A. Gene expression values were normalized and characterized for the significance of overexpression in one group relative to other groups in the comparison. The top 50 genes that are significantly overexpressed in one group are shown. All pre-stasis and post-selection cell types have been used. Analysis was performed in GeneCluster, and the color bar describing how normalized values are depicted is shown at the bottom of the figure. B. Distinct classes of genes over-expressed in post-selection HMEC. Genes showing one of three specific patterns of expression in the four pairs of pre-stasis and post-selection samples are diagramed. The top 10 qualifiers (based on fold change) are shown (some genes are represented by more than one qualifier).

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Molecular Cancer

ISSN: 1476-4598