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Figure 3 | Molecular Cancer

Figure 3

From: Human periostin gene expression in normal tissues, tumors and melanoma: evidences for periostin production by both stromal and melanoma cells

Figure 3

Quantitative analysis of POSTN expression in melanoma. A. POSTN and ACTB cDNA levels were measured in triplicate in normal skin (n = 6), benign nevi (n = 3) and melanoma primary tumors (n = 46) or metastases (n = 67) as described in Fig. 1 legend. Error bars represent SD. B. Data from panel A for normal tissues (N), primary tumors (P) and metastases (M) were classified into six ranges of POSTN/ACTB × 104 values. C. Comparison of POSTN/ACTB × 104 values between metastases and matched primary tumors from 11 patients or between distinct metastases from the same individual (patients LB2174, LB2201 and LB2077, with indication of tumor resection dates as MM.YY). Error bars represent SD. D. Metastatic tumors (Meta) were classified according to their localization (lymph node, liver or (sub)-cutaneous) and POSTN expression levels were compared to levels in tissue samples from normal organs (N). E. POSTN/ACTB × 104 values were measured in hepatic metastatic lesions from intraocular melanoma (Meta) and normal liver.

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Molecular Cancer

ISSN: 1476-4598