Figure 1From: Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expressionEffect of sapphyrins on cell proliferation. A, Structure of sapphyrins. B, A549 and C, PC3 cancer cells were treated with inhibitors for 24 hours, medium was replaced, and relative proliferation measured after an additional 48 hours by tetrazolium salt reduction. The anti-proliferative activity of cisplatin is shown for comparison.Back to article page