Skip to main content

Table 2 Single-dose toxicity in CD1 mice.

From: Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression

Compound

Dose (μmol/kg)

Observed Lethality

PCI-2012

20

1/3

 

30

0/3

 

40

3/3

PCI-2022

30

0/3

 

40

0/3

 

60

3/3

PCI-2050

20

0/3

 

25

0/3

 

30

3/3

PCI-2042

50

1/3

 

60

0/3

 

75

2/3

Back to article page