TY - JOUR AU - Console, Gloria M. AU - Herenu, Claudia B. AU - Camihort, Gisela A. AU - Luna, Georgina C. AU - Bracamonte, Maria I. AU - Morel, Gustavo R. AU - Goya, Rodolfo G. PY - 2008 DA - 2008/01/25 TI - Insulin-like growth factor-I gene therapy reverses morphologic changes and reduces hyperprolactinemia in experimental rat prolactinomas JO - Molecular Cancer SP - 13 VL - 7 IS - 1 AB - The implementation of gene therapy for the treatment of pituitary tumors emerges as a promising complement to surgery and may have distinct advantages over radiotherapy for this type of tumors. Up to now, suicide gene therapy has been the main experimental approach explored to treat experimental pituitary tumors. In the present study we assessed the effectiveness of insulin-like growth factor I (IGF-I) gene therapy for the treatment of estrogen-induced prolactinomas in rats. SN - 1476-4598 UR - https://doi.org/10.1186/1476-4598-7-13 DO - 10.1186/1476-4598-7-13 ID - Console2008 ER -