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Figure 5 | Molecular Cancer

Figure 5

From: Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells

Figure 5

Cell death resistance in response to oxaliplatin treatment. A, Proportion of viable cells after a 72 hour oxaliplatin treatment (0 to 8 μM) of SW480-FlpIn and SW480-PSAT1 cells with a high DNA content (black), in the G2/M phase (white), the S phase (grey), or the GO/G1 phase (white with black dots). B, Pictures of SW480-FlpIn and SW480-PSAT1 cell morphology. Cells were either not treated or treated with 10 μM of oxaliplatin for 24 hours. Staining was done using either DAPI to visualize the nucleus or an anti-tubulin antibody to visualize the entire cell. Giant multinucleated cells are indicated by an arrow. Magnification ×63.

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