Figure 3
From: DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
Gene expression status correlates with promoter methylation status among breast cancer cell lines. Association between RT-PCR expression and MSP methylation status of the six indicator genes for the 12 breast cancer cell lines. Scores were calculated for CEACAM6, CDH1, CST6, ESR1, LCN2, and SCNNIA. Hypermethylator cell lines (black triangles) and low-frequency methylator cell lines (white triangles) demonstrate a statistically significant relationship between gene expression status and promoter methylation status.