Figure 4From: Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesisEffects of curcumin and/TRAIL on cell cycle inhibitors and cyclin D1. (A), Immunohistochemistry was performed to measure the expression of cell cycle inhibitors (p21/WAF1 and p27/KIP1) and cyclin D1 in tumor tissues derived from control and/or treated mice on week 6. (B), Expression of p21/WAF1, p27/KIP1, cyclin D1 and β-actin in tumor tissues derived on week 6 were measured by the Western blot analysis.Back to article page