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Figure 4 | Molecular Cancer

Figure 4

From: Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin

Figure 4

Phenylbutyrate down-regulates BRCA1 expression in head and neck cancer cell lines. Cells were treated with 2 mM phenylbutyrate (PB) for 3 days before the cells were harvested and the levels of BRCA1 protein analyzed with Western blot. The relative amount of BRC1 protein in the phenylbutyrate-treated samples is expressed as a fraction of the BRCA1 protein level in untreated controls.

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Molecular Cancer

ISSN: 1476-4598