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Figure 3 | Molecular Cancer

Figure 3

From: The LIM and SH3 domain protein family: structural proteins or signal transducers or both?

Figure 3

Model of the putative function of LASP-1 as a zyxin recruiting protein. Upper panel: physiological situation with normal LASP-1 expression. Lower panel: pathological situation in an LASP-1 overexpressing cell and subsequent disruption of zyxin signalling. CD44 and Ezrin are integrated into this figure as possible upstream interaction partners because of their close colocalization to LASP-1 and Krp1, albeit neither direct nor indirect interaction has been proved yet.

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