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Table 2 ERCC2 Asp312Asn and ERCC2 Lys751Gln polymorphisms and ovarian cancer risk

From: DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk

Genotype Cases (%) Controls (%) OR (95%CI) ORadj* (95%CI) P value
ERCC2 Asp312Asn
Asp/Asp 21 (41) 458 (46) 1.00 (reference) 1.00 (reference)  
Asp/Asn 28 (55) 418 (42) 1.46 (0.82–2.60) 0.95 (0.62–1.45)  
Asn/Asn 2 (4) 118 (12) 0.37 (0.09–1.51) 0.9 (0.39–2.12) 0.088
ERCC2 Lys751Gln
Lys/Lys 1 (2) 119 (12) 1.00 (reference) 1.00 (reference)  
Lys/Gln 31 (61) 446 (45) 8.27 (1.54–44.43) 1.08 (0.70–1.66)  
Gln/Gln 19 (37) 430 (43) 5.26 (0.86–32.18) 1.16 (0.49–2.75) 0.025
  1. * Adjusted for age