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Table 2 ERCC2 Asp312Asn and ERCC2 Lys751Gln polymorphisms and ovarian cancer risk

From: DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk

Genotype

Cases (%)

Controls (%)

OR (95%CI)

ORadj* (95%CI)

P value

ERCC2 Asp312Asn

Asp/Asp

21 (41)

458 (46)

1.00 (reference)

1.00 (reference)

 

Asp/Asn

28 (55)

418 (42)

1.46 (0.82–2.60)

0.95 (0.62–1.45)

 

Asn/Asn

2 (4)

118 (12)

0.37 (0.09–1.51)

0.9 (0.39–2.12)

0.088

ERCC2 Lys751Gln

Lys/Lys

1 (2)

119 (12)

1.00 (reference)

1.00 (reference)

 

Lys/Gln

31 (61)

446 (45)

8.27 (1.54–44.43)

1.08 (0.70–1.66)

 

Gln/Gln

19 (37)

430 (43)

5.26 (0.86–32.18)

1.16 (0.49–2.75)

0.025

  1. * Adjusted for age