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Table 2 Comparison of GATA3 and ERα meta-analyses, and RT-PCR study

From: Meta-analysis of human cancer microarrays reveals GATA3 is integral to the estrogen receptor alpha pathway

 

GATA3 Oncomine

ERα Oncomine

ESR1

✔

✔

GATA3

✔

✔

TFF1

✔

✔

TFF3

✔

✔

FOXA1

✔

✔

XBP1

✔

✔

IL6ST

✔

✔

KRT18

✔

✔

AR

✔

✔

BCL2

✔

✔

CCND1

✔

✔

RERG

✔

✔

ERBB4

✔

✔

NAT1

✔

✔

SLC39A6

✔

✔

DNAJC12

✔

✔

HPN

✔

✔

CYP2B6

✔

✔

CA12

✔

✔

STC2

✔

✔

ACADSB

✔

✔

LRBA

✔

✔

PTPRT

✔

✔

SULT2B1

✔

✔

MYB

✔

✔

SEMA3B

✔

✔

RET

✔

✔

SLC7A2

✔

✔

RABEP1

✔

 

IGFBP4

✔

 

CGA

✔

 

GJA1

✔

 

PGR

 

✔

RARRES

 

✔

BBC3

 

✔

LOC255743

 

✔

  1. 51 genes were identified as being upregulated in ERα-positive breast tumours in a recent study by Tozlu et al, and are compared with the Oncomine meta-analysis lists for ERα and GATA3, showing a significant overlap. ✔ shows that this gene is represented.
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Molecular Cancer

ISSN: 1476-4598