Figure 4From: Transformation of MCF-10A cells by random mutagenesis with frameshift mutagen ICR191: A model for identifying candidate breast-tumor suppressorsSpectral karyotyping and array comparative genomic hybridization analyses of transformed MCF-10A cells derived from large tumors grown in nude mice. A. SKY analysis of control MCF-10A and transformed MCF10AαL cells. * sign shows chromosomal alterations between control and transformed cells. B. Array CGH of MCf10AαL cells hybridized against control MCF-10A cells shows chromosomal alterations (indicated by arrows) correlated with those identified by SKY.Back to article page