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Figure 1 | Molecular Cancer

Figure 1

From: Identification of metabolites with anticancer properties by computational metabolomics

Figure 1

Diagram representing the rationale of CoMet. (A) The intracellular level of a metabolite X is predicted to be increased in cancer cells when enzymes that produce X are upregulated and/or enzymes that consume X are downregulated in cancer cells. (B) The intracellular level of a metabolite X is predicted to be decreased in cancer cells when enzymes that produce X are downregulated and/or enzymes that consume X are upregulated in cancer cells. See Material and Methods for a complete description of the rules.

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