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Table 4 List of the biological processes as defined by the Gene Ontology that resulted enriched in the list of up-redulated and down-regulated genes in U87-MG and DBTRG-05 by EASE analysis (EASE score, Bonferroni < 0.05)

From: Gene expression time-series analysis of Camptothecin effects in U87-MG and DBTRG-05 glioblastoma cell lines

U87 DOWN

DBTRG DOWN

Cell cycle

Mitotic cell cycle

Mitotic cell cycle

Cell cycle

Cell proliferation

Cell proliferation

Cell growth and maintenance

DNA metabolism

Cellular process

Deoxyribonucleic acid metabolism

DNA replication and chromosome cycle

 

DNA replication

 

S-phase of mitotic cell cycle

 

Mitosis

 

M-phase of mitotic cell cycle

 

DNA metabolism

 

DNA dependent DNA replication

 

Cell cycle checkpoints

 

M-phase

 

Nuclear division

 

G1-S transition of mitotic cell cycle

 

U87 UP

DBTRG UP

Negative regulation of cell proliferation

N.A.

Regulation of cellular process

 

Regulation of biological process

 

Regulation of cell proliferation

 

Response to external stimulus

 

Cell proliferation

 

Response to stress

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