TY - JOUR AU - Denkert, Carsten AU - Budczies, Jan AU - Weichert, Wilko AU - Wohlgemuth, Gert AU - Scholz, Martin AU - Kind, Tobias AU - Niesporek, Silvia AU - Noske, Aurelia AU - Buckendahl, Anna AU - Dietel, Manfred AU - Fiehn, Oliver PY - 2008 DA - 2008/09/18 TI - Metabolite profiling of human colon carcinoma – deregulation of TCA cycle and amino acid turnover JO - Molecular Cancer SP - 72 VL - 7 IS - 1 AB - Apart from genetic alterations, development and progression of colorectal cancer has been linked to influences from nutritional intake, hyperalimentation, and cellular metabolic changes that may be the basis for new diagnostic and therapeutic approaches. However, in contrast to genomics and proteomics, comprehensive metabolomic investigations of alterations in malignant tumors have rarely been conducted. SN - 1476-4598 UR - https://doi.org/10.1186/1476-4598-7-72 DO - 10.1186/1476-4598-7-72 ID - Denkert2008 ER -