Table 2 Estimation of false discovery rate and the number of false positives for three different p-value thresholds. The estimates result from a permutation procedure that is detailed in the material and methods section.
From: Metabolite profiling of human colon carcinoma – deregulation of TCA cycle and amino acid turnover
p-value threshold | number of detected metabolites | False discovery rate (FDR) | Estimated number of false positive metabolites |
|---|---|---|---|
0.05 | 120 | 8.2% | 10 |
0.01 | 82 | 2.3% | 2 |
0.00024 | 24 | 0.2% | 0 |