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Table 3 Association between deletions of the 4 candidate genes in early- and late-onset BC

From: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma

  

Group-A

Group-B

  

PHF2

FANCC

PTCH1

XPA

PHF2

FANCC

PTCH1

XPA

  

D+

D-

D+

D-

D+

D-

D+

D-

D+

D-

D+

D-

D+

D-

D+

D-

PHF2

D+

-

-

9

11

6

14

6

14

-

-

13

12

5

20

6

19

 

D-

  

13

14

8

19

4

23

  

16

18

11

23

6

28

p value

-

0.83

0.98

0.21

-

0.71

0.29

0.55

FANCC

D+

-

-

-

-

5

17

5

17

-

-

-

-

7

22

5

24

 

D-

    

9

16

5

20

    

9

21

7

23

p value

-

-

0.32

0.82

-

-

0.61

0.56

PTCH1

D+

-

-

-

-

-

-

6

8

-

-

-

-

-

-

9

7

 

D-

      

4

29

      

3

40

p value

-

-

-

0.02*

-

-

-

0.00003*

  1. Abbreviations used are: D+: Deletion positive; D-: Deletion negative; * indicates p value significance
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Molecular Cancer

ISSN: 1476-4598