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Table 4 Association between methylation of the 4 candidate genes in early- and late-onset BC

From: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma

  

Group-A

Group-B

  

PHF2

FANCC

PTCH1

XPA

PHF2

FANCC

PTCH1

XPA

  

M+

M-

M+

M-

M+

M-

M+

M-

M+

M-

M+

M-

M+

M-

M+

M-

PHF2

M+

-

-

6

4

2

8

4

6

-

-

10

3

7

6

5

8

 

M-

  

8

29

13

24

4

33

  

13

33

14

32

9

37

p value

-

0.02*

0.36

0.03*

-

0.001*

0.12

0.16

FANCC

M+

-

-

-

-

6

8

7

7

-

-

-

-

7

16

7

16

 

M-

    

9

24

1

32

    

14

22

7

29

p value

-

-

0.29

0.0001*

-

-

0.51

0.33

PTCH1

M+

-

-

-

-

-

-

4

11

-

-

-

-

-

-

9

12

 

M-

      

4

28

      

5

33

p value

-

-

-

0.23

-

-

-

0.01*

  1. Abbreviations used are: M+: Methylation positive; M-: Methylation negative; * indicates p value significance
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Molecular Cancer

ISSN: 1476-4598