Table 5 Immunohistochemical expression of FANCC and PTCH1 with respect to their alterations
| Â | FANCC alteration | Â | PTCH1 alteration | Â |
|---|---|---|---|---|
Sample No. | Deletion/Methylation | FANCC protein expression | Deletion/Methylation | PTCH1 protein expression |
1186 | +/- | - | -/- | +++ |
374 | -/+ | - | -/+ | - |
4187 | +/- | + | -/+ | - |
3266 | +/+ | - | -/- | +++ |
5451 | -/- | +++ | -/- | +++ |
5596 | -/- | +++ | -/+ | - |
3156 | +/+ | - | -/- | +++ |
4604 | +/+ | - | +/+ | - |
4131 | -/+ | ++ | +/- | - |
2490 | +/- | - | -/+ | - |
2400 | +/+ | - | -/+ | ++ |
796 | +/- | ++ | -/+ | - |
880 | -/- | +++ | +/+ | - |
314 | +/- | ++ | +/- | ++ |
5337 | +/- | - | -/- | +++ |
1865 | +/+ | - | -/+ | - |
4671 | -/- | +++ | +/- | + |
3025 | +/+ | - | -/+ | - |
6155 | -/+ | - | -/- | +++ |
1144 | -/- | +++ | -/+ | - |
P value | P = 0.004 * | P = 0.001 * | ||