Table 1 Five most up and down regulated miRNAs in each tumour area compared to normal thyroid epithelium.
Up-regulated miRNAs | ||||
|---|---|---|---|---|
Classic PTC | Insular Carcinoma | Anaplastic Carcinoma | Lymphocytic Infiltrate | Vascular Invasion |
mir-221 | mir-221 | mir-221 | mir-221 | mir-221 |
mir-324-5p | mir-486 | mir-205 | mir-205 | let7e |
mir-93 | mir-205 | mir-324-5p | mir-378 | mir-412 |
mir-182* | let7e | mir-486 | let7e | mir-15a |
mir-378 | mir-320 | mir-93 | mir-15a | mir-497 |
Down-regulated miRNAs | ||||
Classic PTC | Insular Carcinoma | Anaplastic Carcinoma | Lymphocytic Infiltrate | Vascular Invasion |
mir-124a | mir-124a | mir-328 | mir-328 | mir-328 |
mir-192 | mir-520e | mir-149 | mir-124a | mir-423 |
mir-UL148D-1 | mir-345 | mir-520e | mir-192 | mir-518a-2* |
mir-let-7g | mir-7 | mir-375 | mir-152 | mir-124a |
mir-let7f | mir-140 | mir-124a | mir-127 | mir-152 |