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Figure 6 | Molecular Cancer

Figure 6

From: LIM only 4 is overexpressed in late stage pancreas cancer

Figure 6

LMO4 expressions in the IPMA-IPMC pathway, including 6 normal ductal epithelial ducts, 13 IPMA lesions, 15 IPMB lesions and 8 IPMC lesions (5 for invasive IPMC and 5 for non-invasive IPMCs). IPMC cells expressed significantly higher levels of LMO4 (mean, 1.79; 95% CI, 0.99 – 2.58) than did IPMB (mean, 0.98; 95% CI, 0.69 – 1.27) (p = 0.003), IPMA (mean, 0.60; 95% CI, 0.47 – 0.73) (p < 0.001), or normal ductal epithelial cells (mean, 0.65; 95% CI, 0.34 – 0.95) (p < 0.001). The differences in LMO4 expression between IPMB and IPMA cells (p = 0.09), IPMB and normal ductal epithelial cells (p = 0.2) and IPMA and normal ductal epithelial cells (p = 0.9) are not significant. The bottom and the top edges of the box mark the lower bound and upper bound of the 95% Confidence Interval for the Mean, respectively. The center horizontal line is drawn at the sample mean. The center vertical lines drawn from the boxes extend to the minimum and the maximum. Expression of LMO4 mRNA was normalized to that of 18S rRNA.

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