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Figure 5 | Molecular Cancer

Figure 5

From: A combination of indole-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy

Figure 5

3-MA does not inhibit the cell death caused by co-treatment with I3C and genistein. Cell viability (A) and the sub-G1 population (B) in the HT-29 cells exposed to DMSO, 3-MA (10 mmol/L) or the co-treatment with I3C (300 μmol/L) and genistein (40 μmol/L) with or without 3-MA (10 mmol/L) for 48 h. Cell viability and the sub-G1 population were analyzed as described in Materials and Methods. Columns, mean (n = 3); bars, SD. *, P < 0.05, significantly different compared with the DMSO-treated control.

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Molecular Cancer

ISSN: 1476-4598