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Figure 3 | Molecular Cancer

Figure 3

From: Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis

Figure 3

Comparison of inflammatory infiltrates in tumor-bearing BALB and BALBLps-dmice 27 wks post carcinogen. A. Total BALF macrophages, lymphocytes, epithelial cells and protein recovered from BALB and BALBLps-dmice after MCA or MCA/BHT treatment. Significant increases in inflammation in tumor-bearing mice were found in BALBLps-dcompared to BALB mice. Mean and SEM are presented; n = 6 mice/experimental group. P values are indicated on the graphs for each phenotype (macrophages, lymphocytes, epithelial cells, and total protein); comparisons are between MCA/BHT treatment groups and MCA/oil vehicle or between BALB and BALBLps-dmice. B. Immunohistological staining in BALB and BALBLps-dmice after 27 wks after MCA/BHT treatment for macrophages and T-lymphocytes using F4/80 and CD3 markers, respectively. Bar indicates 100 μm. Slides were counterstained with hematoxylin.

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