Figure 4
Analysis of protocol 2 genes increased in the BALBLps-d tumors compared to BALB tumors. Supervised and unsupervised bioinformatic methods were used for these analyses. A. Cluster 4 identified using statistical (Genespring) analysis. Each vertical line represents one sample for each strain for an n = 2 (Un = uninvolved, MCA = 3-methlycholanthrene, and for BALBLps-dtumor) with the exception of BALB tumor (n = 1), indicated by the small horizontal black line above each treatment on the x-axis. B. Profile (Spotfire) analysis similar to that of cluster 4. Z-score (y-axis) is the intensity in terms of standard deviations (SD) from the mean. The z-score is calculated by subtracting the mean and dividing by the SD for each probeset. See Additional file 6, Figure S3 for supervised and unsupervised analysis depicted as heat maps.