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Table 1 Metastasis of LoVo-C and LoVo-P Cells in Nude Mice BALB/c

From: PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin β1-ERK1/2 and-MMP2 signaling

Group Total number of mice Number of mice with metastasis Number of metastatic foci
LoVo-C uninfected 8 0 0 *
LoVo-P uninfected 8 4 13
LoVo-P lentivirus-control 8 4 8
LoVo-P lentivirus-integrin β1 8 1 1 *
LoVo-P lentivirus-PRL-3 8 1 1 *
  1. *P < 0.05 when compared to LoVo-P lentivirus-control
  2. Statistical analysis was performed with Poisson distribution events test
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Molecular Cancer

ISSN: 1476-4598