Inhibition of hypoxia-induced VEGF secretion. ME-180 cells were pre-treated with NCGC00043898, NCGC00044926, NCGC00049606 and NCGC00056044 at various concentrations for 5 min and then exposed to 15 μM iodochorohydrozyquinoline for 17 hrs. Then VEGF level was determined by human VEGF ELISA kit. Representative values are from a single experiment performed in duplicate. Data are expressed as mean ± SD.