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Table 2 Summary of compound activities (IC50, μM) in HRE-bla assay induced by ≤1% oxygen or CoCl2

From: Identification of small molecule compounds that inhibit the HIF-1 signaling pathway

Cluster

Compound ID

CoCl2

≤1% Oxygen

Singleton

NCGC00033933

0.013

0.84

Singleton

NCGC00053249

5.62

14.8

71

NCGC00056044

3.16

1.56

23

NCGC00078922

6.31

Inactive

31

NCGC00044926

0.50

0.17

31

NCGC00043631

0.50

0.11

27

NCGC00043836

2.51

0.39

39

NCGC00043898

2.82

1.22

39

NCGC00044763

2.51

1.10

39

NCGC00049606

3.16

0.75

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Molecular Cancer

ISSN: 1476-4598