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Table 2 Summary of compound activities (IC50, μM) in HRE-bla assay induced by ≤1% oxygen or CoCl2

From: Identification of small molecule compounds that inhibit the HIF-1 signaling pathway

Cluster Compound ID CoCl2 ≤1% Oxygen
Singleton NCGC00033933 0.013 0.84
Singleton NCGC00053249 5.62 14.8
71 NCGC00056044 3.16 1.56
23 NCGC00078922 6.31 Inactive
31 NCGC00044926 0.50 0.17
31 NCGC00043631 0.50 0.11
27 NCGC00043836 2.51 0.39
39 NCGC00043898 2.82 1.22
39 NCGC00044763 2.51 1.10
39 NCGC00049606 3.16 0.75