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Figure 2 | Molecular Cancer

Figure 2

From: The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth

Figure 2

All the SHH signaling pathway components are expressed in human CRCC tumors. (A) Western blot analysis of the SHH ligand in 9 human tumors (T1 ...) and normal corresponding tissues (N1 ...) lysates incubated with antibodies against human SHH ligand and corresponding β-actin. The gels shown are representative for at least 3 independent experiments. (B) Quantitative gene expression of Ptch1 and Smo receptors, and of the Gli1 transcription factor in the same normal/tumoral tissue pairs shown in (A). Results are representative of 4 independent experiments.

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