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Figure 7 | Molecular Cancer

Figure 7

From: Intrinsic chemoresistance to gemcitabine is associated with constitutive and laminin-induced phosphorylation of FAK in pancreatic cancer cell lines

Figure 7

Effects of FAK RNAi and FRNK overexpression on LN-mediated FAK and Akt activation. After replating on plastic or LN for 1 h, parental AsPC-1 cells and FAK RNAi2-transfected pool cells (i-Pool) (A), pcDNA3.1-FRNK-transfected pool cells (Pool) (B) and their respective vector-transfected clones (i-Vector, Vector) were collected and used for western blot analysis to detect the expression of pFAK (pY397), p-Akt (pS473) and their total proteins. The membranes were probed with anti-β-actin antibody to ensure even loading of proteins in each lane.

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Molecular Cancer

ISSN: 1476-4598